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Cell 175:1634-50e17

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The TJ and gut permeability The TJ (also referred to as zonula occludens ) is the most apical cell-to-cell adhesion between neighboring epithelial and endothelial cells

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For example, individual studies may be of high quality but if findings are contradictory or samples do not generalize well to the patient population addressed by the guideline, then evidence strength may be downgraded

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